Mobility and Cognition in Seniors. Report from the 2008 Institute of Aging (CIHR) Mobility and Cognition Workshop

Manuel Montero-Odasso, MD, PhD, AGSF, FRCPC,1,23, Louis Bherer, MPS, PhD4, Stephanie Studenski, MD, MPH, AGSF5, Karen Gopaul, MSc1, Afua Oteng-Amoako, OD, MPH, MSc1, Sarah Woolmore-Goodwin, MSc2, Paul Stoole, PhD6, Jennie Wells, MD, FRCPC, FACPA2, Timothy Doherty, MD, PhD, FRCPC6, Aleksandra A. Zecevic, PhD7, David Galinsky, MD8, R. Jane Rylett, PhD, FCAHS9, Jeffrey Jutai, PhD10, Susan Muir–Hunter, PT, PhD17, Mark Speechley, PhD3, Richard Camicioli, MD, FRCPC11

1Gait and Brain Lab, Parkwood Institute and Lawson Health Research Institute, University of Western Ontario, London, ON;
2Division of Geriatric Medicine, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON;
3Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON;
4Department of Psychology and PERFORM Center, Concordia University, Montreal, QC;
5Translational Gerontology Branch Longitudinal Studies Section, National Institute on Aging, Bethesda, MA, USA;
6Department of Physical Medicine and Rehabilitation, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON;
7School of Health Studies, University of Western Ontario, London, ON;
8Ben-Gurion University of the Negev, Beer-Sheva, Israel;
9Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON;
10Faculty of Health Sciences, Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, ON;
11Faculty of Medicine and Dentistry, Department of Medicine, Division of Neurology, University of Alberta, Edmonton, AB

DOI: http://dx.doi.org/10.5770/cgj.18.188


Background

The annual Scientific Meeting of the Canadian Association on Gerontology was held on October 24 and 25, 2008 in London, Ontario. Prior to the annual meeting, mobility and cognition experts met on October 23, 2008 to engage in a pre-conference workshop.

Methods

Discussions during the workshop addressed novel areas of research and knowledge and research gaps pertaining to the interaction between mobility and cognition in seniors.

Results

Workshop presenters moved from the neuromuscular, biomechanics, and neurology of gait impairments, and falls through the role of cognition and mood on mobility regulation to the whole person in the environment. Research gaps were identified.

Conclusions

Despite a consensus that mobility and cognition are increasingly correlated as people age, several gaps in our understanding of mechanisms and how to assess the interaction were recognized. The gaps originally identified in 2008 are still pertinent today. Common and standardized assessments for “mobility and cognition” are still not in place in current practice. Interventions that target mobility and cognitive decline as a single entity are still lacking.

Key words: mobility, executive function, dual-task gait, exercises, gait variability, falls, MCI, Parkinson’s disease

INTRODUCTION

“By bringing his body up into a vertical position, modifying his hands in one way and his feet in another, and by improving his brain still further and using it as hard as he could, he stood a chance of success.”

-Desmond Morris, “The Naked Ape”: A Zoologist’s Study of the Human Animal. McGrawHill, 1967, p.25.

The development of human intelligence is marked by the evolutionary achievement of bipedalism and encephalization. Bipedalism played an essential role in enabling the process of encephalization. As described by Desmond Morris, the achievement of upright walking allowed ancient apes to use their hands during locomotion, an essential step for the creation of hand tools and hunting weapons. This also spurred the subsequent incorporation of more protein into the diet of Homo sapiens, which ultimately contributed to develop larger and complex brains.

Upright bipedal walking and subsequent encephalization are complex features in human evolution and are quintessential hallmarks of the human body.(1) Consequently, and not surprisingly, the functional decline associated with aging originates from two sophisticated and complex human achievements: cognition and gait.(2) As we age, two major geriatric syndromes, cognitive impairment and mobility limitations, become prevalent and burden our quality of life. Extreme manifestations of these syndromes are dementia and falls. Interestingly, these manifestations often coexist in elderly people; dementia affects 30% of Canadians over age 80, and falling is a common geriatric syndrome affecting 30% of older adults over age 65 each year.(3)

Evidence shows that cognition and mobility are intertwined.(4) Elderly people with cognitive problems have been found to have a 10 to 15 times greater risk of developing Alzheimer’s disease (AD), as well as a higher risk of mobility decline and falling, compared to cognitively normal seniors.(57)

Cognitive function plays a key role in the regulation and control of even routine walking, especially in older adults. Attention is a necessary cognitive resource for maintaining normal walking and navigation, and attentional deficits are independently associated with postural instability, impairment in performing activities of daily living, and future falls.(8) The role of cognition in walking is ultimately more marked in people with cognitive problems.(9,10)

In order to untangle this interesting relationship, we were fortunate to have local and international experts in the field who presented their innovative research on mobility and cognition. The main focus of the workshop was to describe and better understand the interaction between gait and cognition, which may point to new strategies and interventions that delay mobility dysfunction and cognitive decline. Speakers’ presentations ranged from the epidemiology and cellular mechanisms related to mobility, muscle function and neurocognitive control of mobility, through to neuromuscular biomechanics and the neurology of falls; finally, to the whole person in the environment including intelligent assistive devices.

This workshop provided a seminal forum in which research on “mobility and cognition” in older adults was examined with key experts in the field. Several important research gaps were identified and the clear necessity for the translation of research knowledge to levels of care was emphasized. Despite research progress in the areas of “mobility and cognition” in older adults since this 2008 workshop, the research gaps identified then remain highly relevant today.

Background

Over the next 20 years there will be a substantial increase in the number of Canadians aged 65 and older.(11) Increased life expectancy is often accompanied by disability, stemming in a large part from two major geriatric syndromes: mobility and cognitive impairment. It has been demonstrated that the decline in gait velocity is a preclinical marker of diseases.(1215) Similarly, aging is associated with decreases in cognitive function and the development of dementia. Eight per cent of Canadians aged 65 and older meet the criteria for dementia, and this prevalence increases to 35% in people over the age of 85.(1618) Furthermore, mobility and cognitive impairment appear to become more related as people age.(1921) Specifically, gait slowing and dementia often co-exist in the same individual, have been attributed to changes in specific brain regions,(2225) and may contribute to an increased risk of falls and disability.(26,27)

Workshop Themes

Objectives

  1. Provide an overview of the state of understanding and research in mobility and cognition;

  2. Explore the value of the dual-task gait as a way to evaluate cognitive and mobility relationships;

  3. Investigate interventions to improve mobility and cognitive impairments as a solo entity in seniors; and

  4. Identify the knowledge gaps and strategic research priorities in mobility and cognition, in support of the Mobility in Aging initiative from the CIHR, Institute of Aging.

Participants

There were 70 workshop participants and 12 speakers and moderators. Participants were researchers, physicians, and allied health clinicians with expertise in elderly care. For a list of speakers and moderators, and an evaluation summary of the workshop, see Appendix A.

RESEARCH PRESENTATIONS AND SPEAKERS

The workshop was opened with welcome remarks by Dr. Jane Rylett of the University of Western Ontario and Chair of CIHR-IA Advisory Board who highlighted the research priority on mobility and aging as part of the CIHR Institute of Aging. Dr Manuel Montero-Odasso moderated the workshop. The following are summaries of the research presentations in order of presentation.

Epidemiology of the relationship between mobility and cognition. Is mobility a predictor of cognitive decline?

Dr. Stephanie A. Studenski, University of Pittsburgh, Pittsburgh, PA, USA

Among older adults, cognitive and movement disorders co-occur more frequently than would be expected by chance, and the presence of either disorder increases the risk of onset of the other. Epidemiological evidence supports associations between cognition, movement and mood both cross-sectionally and longitudinally. Additionally, cognition, movement, and mood are associated with identifiable brain abnormalities such as cerebral white matter disease.(28) In a model proposed by Dr. Studenski’s group, regions of ischemia or leukoariosis in white matter or atrophy in regions of grey matter can result in psychomotor slowing which culminates in disorders of cognition, movement, and mood that ultimately lead to functional decline and falls. Since the decline in cognition and depressive symptoms are both associated with slower gait and falls, future studies of aging should include combined measures of movement, cognition, and mood, as should prevention and intervention studies. For future research, animal model studies could help us better understand the mechanism behind these associations.

Neuromuscular changes associated with poor mobility and aging

Dr. Timothy Doherty, Western University, London, ON, Canada

Aging is associated with substantial decline in neuromuscular function. This is best characterized by loss of muscle mass and strength in distal and proximal muscles in the upper and lower limbs — a phenomenon referred to as “sarcopenia”.(29,30) Aging is also associated with significant differences in the contractile properties of skeletal muscle, characterized by slowing for both contraction and relaxation speeds. Peripheral fatigue may be somewhat less in the older adult’s skeletal muscle, particularly when measured relative to maximal force values. The underlying cause of sarcopenia is multifactorial, but age-associated loss of motor units with incomplete re-innervation appears to be a major influence.(30) Other factors include disuse, nutritional deficiency, inflammatory effects, and hormonal factors. Neuromuscular function and sarcopenia have a direct impact on mobility and falls. The loss of strength, and slower contractile speed which results in less power of lower limb muscles, are major factors that contribute to poor mobility in the elderly.

Balance performance, behaviour and cognition. The impact on falls

Dr. Aleksandra Zecevic, Western University Ontario, London, ON, Canada

Cognitive impairment reduces central nervous system (CNS) ability to process and integrate multiple sensory inputs which results in balance problems, increased postural sway, and slower walking speed; however, causes of falls among cognitively impaired individuals are still poorly understood. A Seniors Falls Investigative Methodology (SFIM) was created to investigate falls in seniors which shifted the focus from the faller to the system in which the person functions.(31,32) Studies in a community, hospitals, and long-term care facilities identified psychological contributors to falls that include poor decision making, cognition, and attention. One way to manage and prevent falls and injuries in individuals with dementia is to accept fallers as they are and build a safe system that will accommodate them. This requires removing preconditions that lead to falls, improving and optimizing formal and informal supervision, and establishing safety barriers through policies and practices in all organizations involved in care of patients with cognitive impairments. System-wide interventions and safety improvements should be integrated into health-care organizations and the community in order to ensure safe mobility in elderly Canadians.

Assistive devices for mobility and cognition. Can we have a unified approach? The role of cognition in assistive technology for mobility

Dr. Jeffrey Jutai, University of Ottawa, Ottawa, ON, Canada

Assistive devices, such as canes, walkers, and wheelchairs, are very commonly used with older patients who have mobility difficulties.(33) In recommending devices, clinicians attend first to the physical capabilities and limitations of their patients. Evidence indicates that impaired cognitive processes, particularly cognitive flexibility and working memory, are prevalent in older people and associated with falls. Impaired cognition affects proper utilization of mobility devices and increases the risk of falls due to reduced attentional capacity, impaired central processing and integration, impaired judgment, and self-regulation and execution of postural responses, resulting in impaired balance, gait, anticipatory postural adjustments, and reactive postural responses. The effects of patients’ cognition on decisions about mobility devices are poorly understood. Successful device-assisted rehabilitation and management of mobility difficulties may require strategies that target both physical functions and cognitive processes. Important research questions that address gaps in this area include: 1) Are elderly rehabilitation patients with impaired executive-controlled processes significantly more likely to report problems with the safety and effective use of mobility devices? 2) Is cognitive impairment reliably correlated with the decision to recommend or not the use of mobility assistive devices? 3) Do the relationships among cognition, mobility, and device use change predictably over time? 4) What are the opportunities for improving the usefulness of theory-derived cognitive assessments in making decisions about the selection of mobility assistive devices?

History of the mobility and gait analysis in geriatric research

Dr. David Galinsky, Ben Gurion University, Be’er Sheva, Israel

Prof. Bernard Isaacs established the concept of the ”giants” in geriatric medicine: Immobility, Instability, Intellectual, and Incontinence.(34) One of the main negative outcomes of the giants is falls. Gait assessment procedures used to detect risk of falls have required considerable investment in equipment for sophisticated biomechanical testing, limiting the use of gait testing procedures to the laboratory or clinics. We pioneered a simple gait assessment using an effective method for home and community assessment: the ELGAM (extra-laboratory gait assessment method).(35,36) A study was conducted on residents of a sheltered housing for seniors ranging in age from 63–90 years. A complete geriatric comprehensive assessment was performed and a neurological and physical exam that included the ELGAM was administered.(37) Through ELGAM, slow walking, small steps, impaired balance, and difficulty turning the head were all significantly associated with unstable gait and, therefore, falls. The ELGAM was an efficient and effective method of recording gait and the early detection of risk of falls.

Gait impairment and Parkinsonism: Risk factors for cognitive decline & dementia

Dr. Richard Camicioli, University of Alberta, Edmonton, AB, Canada

Mild Parkinsonism and gait impairment occur prior to the development of mild cognitive impairment, which is a precursor to dementia. Age-related gait changes may be explained by co-morbid conditions, including vascular disease, which increases the risk of cognitive decline and dementia. However, cognitive and mobility changes can be part of the spectrum of degenerative disease in the absence of illness or frailty and, in some cases, remain unexplained. Longitudinal studies can help determine if specific aspects of cognitive decline are related to Parkinsonism and gait impairment. Indeed, the pathology of age-related gait impairment was shown to correlate with nigral neurofibrillary tangle count, while Parkinson’s showed similar correlations. Specific degenerative diseases associated with aging, such as dementia with Lewy bodies and Parkinson’s disease, are also characterized by Parkinsonism and are associated with cognitive decline and gait impairment.(3840)

Gait and dual-tasking. Is it the new paradigm to explore mobility and cognition in older people?

Dr. Manuel Montero-Odasso, Western University, London, ON, Canada

A seminal study, “stop walking while talking”, demonstrated that the inability to maintain a conversation while walking is a marker for future falls in older adults.(41) Walking while performing a secondary task (dual-task paradigm) has become the classic way to assess the interaction between cognition and gait. Previous research has described the effect of dual-tasking on gait performance, showing specific associations between slowing gait and executive dysfunction and attention deficits. Results from our “Gait and Brain Study” demonstrate that impairments in specific cognitive domains — attention, executive function, and working memory — are associated with slow gait velocity and slower gait velocity under dual-task conditions, and higher variability indicating that those specific cognitive domains are crucial for maintaining normal gait performance.(42,43) Therefore, gait variability under dual-tasking may be a sensitive measure of Mild Cognitive Impaired seniors at risk of developing dementia and risk of falling.(9)

Effect of exercise on cognition in older adults

Dr. Louis Bherer, Université de Québec à Montréal et Institut universitaire de gériatrie de Montréal, Montreal, QC, Canada

An increasing number of studies suggest that physical activities might protect against age-related cognitive decline. In fact, aerobic training leads to a significant improvement in VO2 max that correlates with increased cognitive performances in sedentary older adults,(44) with larger benefits on attentional control functions, as required, to share attention between multiple tasks. To further assess the impact of physical activity on cognitive performances in older adults, we conducted cross-sectional and intervention studies involving various populations of older adults, from sedentary and frail older adults(45,46) to athletes or highly active individuals who engage in intense fitness training programs.(45) In our cross-sectional study we found that being physically active can protect against decline in cardiorespiratory fitness, as well as less of a decline in dual task performance.(46) Our intervention studies, designed for sedentary older adults, demonstrate that just three months of physical exercise can improve physical health and attentional control functions in older adults and even frail older adults.(45)

Tai Chi as an intervention on cognition. A review of the evidence

Dr. Jennie Wells, Western University, London, ON, Canada

Tai Chi is growing in popularity in western culture as a form of exercise, relaxation and health therapy. It has been shown to improve cardiovascular fitness, blood pressure, immunity, balance, and reduce falls, LDL cholesterol, pain, anxiety, and depression. Tai Chi may also benefit cognition since it is a form of aerobic exercise and reduces depression and stress, both of which impair cognition. However, a wider variety of research strategies are needed to support evidence that Tai Chi is beneficial for cognition. Designing research studies that involve Tai Chi as an intervention can be challenging since it is a multi-component pluralistic intervention which can vary, depending on individual participation, duration of practice, and frequency. A “whole system” approach that recognizes the complex interactions of Tai Chi and utilizes multiple disciplines to conduct and analyze the data would be the best approach.

Round Table: Mobility and Cognition in Older Adults

Several research gaps were identified from the workshop and were grouped under five themes. Future actions discussed were also included in each theme. A synopsis including key points, main gaps, and future directions addressed during the round table is summarized in Figure 1.

 


 

FIGURE 1. Key points, gaps encountered, and future actions discussed in the workshop

1. Understanding the neurobiology of mobility decline

When examining the neurobiology of mobility decline and falls, the panel noted pre-existing knowledge that age-associated muscle loss (sarcopenia), deficits in neural control of gait and balance, chronic nutrient deficiencies (including Vitamin D), polypharmacy and impaired cardiovascular regulation (affecting postural control of blood pressure) are important contributors to falls among older people. Age-related decline is multi-factorial, suggesting a single problem identification is not likely to be useful for diagnosis or detection of falls. Dr. Doherty noted that sarcopenia is not necessarily correlated with the risk of falling; rather, it is neuromuscular function (strength, power, balance) in combination with sarcopenia that appears to have a direct impact on mobility and falls.(47) The interaction of these two phenomena needs to be further explored to better understand challenges in mobility in later life. The role of the CNS, including the integration of sensory inputs, in mobility decline and falls is an emerging area of research. As elderly people continue to age, they become more dependent on their visual cues and less reliant on other senses. These sensorial changes have negative consequences on the neural regulation of mobility as seniors on average have poorer vision and vestibular impairments, which affect the regulation of their balance and mobility. Dr Montero-Odasso highlighted that dual-task gait is a paradigm which can help to evaluate the effect of cognitive resources on mobility and gait performance. Recently, it has become evident that higher level cognitive functions also have a critical role in the regulation of routine walking. Falling itself is not only an issue of the physical mechanics of movement, but the failure of a dual-process that requires thinking about movement and then performing the movement in the context of navigation through the environment.

2. The effect of physical exercise on cognition in vulnerable populations

We are still not fully aware of the mechanisms by which physical activity and exercise influences cognition, and research in this area is just emerging. Consequently, we were not able to identify the best protocol or recommendations for prescribing exercise interventions for preventive purposes or know for whom such preventions might positively enhance cognitive performance. Moreover, research studies targeting vulnerable populations, such as those with mild cognitive impairment (MCI), are lacking. Previous work has established that physical activity protects against cognitive decline. In corroboration, Dr. Bherer presented data from studies indicating better cardiorespiratory fitness (measured as oxygen consumption (VO2max) is predictive of cognitive performance over a six-year period of follow up. Similarly, interventional studies in which participants are assigned randomly to aerobic training (e.g., walking and/or biking) suggest cardiorespiratory fitness plays a causal role in building cognitive reserves.

Future research should focus on the effects of different exercise programs on cognitive domains such as attention and memory, especially because attention and executive function deficits have been strongly associated with risk of falling. This approach will also advance preventive practice if physical fitness measures are considered in the assessments of falls risk.

3. Interrelation and interventions for cognition, mobility and mood

While the panel during the roundtable determined there should be a concerted movement toward understanding the central neural basis of mobility, particularly structural and functional brain changes after exercise interventions, it was proposed that interventions should have targets on the bio-psycho-social domain. This will require identification of contributing factors to falls beyond the capacities and characteristics of the person who fell, as described by SFIM.

Dr. Wells demonstrated from her literature review that implementation of Tai Chi into a senior’s daily routine yields improvements in muscle strength, balance, and mood. Other types of interventions, such as seen in research by Dr. Montero-Odasso, show that nutritional supplements such as vitamin D, which targets the brain and skeletal muscle, can be useful interventions for improving mobility in older adults with vitamin D deficiency.(48)

While emerging evidence indicates physical activity, exercises, and balance training reduce the risk of falls, improve cognition, and enhance dual-tasking, clinicians are finding barriers to adopt this intervention into their practice. It was concluded that more needs to be done to ensure knowledge based on research evidence becomes implemented in clinical practice. Consensus statements and clinical guidelines may help to translate the evidence from research studies to daily practice.

4. Scientific design, level of analysis, and common measures

Presenters agreed on the need for a consensus on how to design future research on mobility and cognition. Cognitive and mobility decline are multi-factorial problems which can be addressed at different levels and with both quantitative and qualitative methodologies.

Future research on the longitudinal pathophysiology should include intermediate outcomes as proxies of mobility and cognition that lead to falls to understanding potential mechanisms. Case-study approach to investigations of system-wide true causes of falls, proposed by Dr. Zecevic, is of special interest for falls in individuals with advanced cognitive impairment.

Unified approaches to understanding the relationships among mobility, cognition, and mood are scarce. Because mobility and cognitive decline are complex phenomena, multi- or trans-disciplinary approaches will likely be the most effective. Such studies would include measures of mobility, cognition, and mood in the same design rather than treating them as unrelated outcomes. Future research that uses physical performance measurements, cognitive measures, and neuroimaging may also help to overcome this challenge. Work in this area will require effective collaborations across disciplines. One of the main gaps identified was the lack of a common language and standardized assessments between researches in the fields of mobility, cognition, and mood.

5. Determining the most appropriate approach for early detection

Early detection of risk was another gap that emerged from the day’s discussions. Dr. Montero-Odasso postulated that gait performance can be seen as a final common pathway that integrates several systems including the cardiovascular, neuromuscular, and neurological. Accordingly, gait assessment can be utilized as a screening tool to detect those older individuals at higher risk of mobility and cognitive decline. A wealth of evidence supports that gait velocity and dual-task gait tests can be used as instruments to detect early changes in cognitive and mobility decline. However, there is no consensus on which is the ideal gait screening measure. A key gap in current research is that we do not have an accepted standard measure of mobility impairment and fall risk that will accommodate the heterogeneity of the older population.

Future Directions

“If we look ten years ahead, what strategies should we consider toward advancing this knowledge from a Canadian perspective? Do we look at mechanisms, interventions, neural correlates? What will make a difference for our seniors and the way we treat, assess, and prevent mobility and cognition decline?”

The panel’s unanimous response to this question, raised by Dr Michael Borrie (Western University), was that novel techniques, such as new developments in brain imaging and quantitive motion/gait analysis, will likely advance our understanding of the physiological basis of the relationship between gait, mood, and cognition. It was also suggested that the different bio-psycho-social research areas should not be seen as competing interests, but be integrated into future research approaches. Each domain must be cared for, as the basis for patient/resident-centered focus and care. The most beneficial way forward would be to determine closely related areas and study them together in order to observe their critical interactions.

Dissemination of the knowledge from researchers and experts should be more effectively applied to clinical practice. This is a serious challenge in the care of the elderly. Ideally, front-line staff, as experts working in the field, will be included in research collaboration from the conceptualization of new research projects.

In the future, our health-care system will become increasingly taxed with the influx of seniors and for the disability stemming from cognitive and mobility declines. To circumvent this mounting stress on seniors and the health-care system, we need to support the creation of a culture that enables people of all ages to exercise both the mind and the body.

At a social and governmental level, we would need to educate policy makers about the needs for — and benefits of — preventing health decline before it becomes unmanageable at any level of care provision.

CONCLUSIONS AND REVISITING THE WORKSHOP SIX YEARS LATER

This workshop provided a seminal environment in which research on “mobility and cognition” in older adults was examined with key Canadian and international experts. Several important research gaps were identified and the clear necessity for the translation of research knowledge at primary care levels was emphasized. Despite research progress in the areas of “mobility and cognition” in older adults since this 2008 workshop, the research gaps identified remain extremely relevant today.

One of the main gaps identified — the lack of a common language and standardized assessments between researches in the fields of mobility, cognition, and mood — still needs to be overcome to better coordinate research and communicate results. This workshop served to seed an initial Pan-Canada collaboration which was crystalized in 2012 in the Mobility, Exercise and Cognition team aggregated under the Canadian Consortium in Neurodegeneration and Aging, funded by CIHR.

Our goal as researchers, community healthcare workers, front-line staff, and physicians is to ensure quality of life and disability free life for our Canadian seniors. This forum was an initial step to ensure action is taken and research is disseminated to those who will benefit from it directly.

ACKNOWLEDGEMENTS

This workshop would be impossible without the constant assistance of Ms. Sarah Woolmore-Goodwin, research assistant from Parkwood Hospital, and the logistic and intellectual support of Dr. Susan Crawford and Ms. Rowena Tate from Institute of Aging (CIHR). We thank the ARGC-Lawson and its Director, Dr. Rob Petrella for their support with this workshop. Very special thanks to Saskia Sivananthan for her contribution on the workshop report sent to CIHR. Finally, we thank the assistance of Drs. Stole and Petrella as associated moderators.

CONFLICT OF INTEREST DISCLOSURES

The authors declare that no conflicts of interest exist. This workshop was sponsored by the Institute of Aging (CIHR) and co-sponsored by the Lawson Research Institute (London, Ontario & Western University). Dr Montero-Odasso’s program in “Gait and Cognition” is funded by CIHR, operating grant MOP12243.

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Correspondence to: Manuel Montero-Odasso, md, phd, agsf, frcpc, Gait and Brain Lab at the Parkwood Institute and Lawson Health Research Institute, Division of Geriatric Medicine at the Schulich School of Medicine & Dentistry, and the Department of Epidemiology and Biostatistics, University of Western Ontario, 801 Commissioners Rd. E., Rm A-280, London, ON N6C 5J1, Canada, E-mail: mmontero@uwo.ca

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APPENDIX A

Workshop members

This is a complete list of the moderators, speakers, facilitator, and administrators. Dr. Anne Martin-Matthews (Scientific Director of the Institute of Aging CIHR), Rowena Tate and Dr. Susan Crawford (Assistant Director of CIHR-IA), Manuel Montero-Odasso (workshop leader and moderator), Paul Stole and Rob Petrella (associate moderators), Sarah Woolmore-Goodwin (research assistant and administrative support), Dr. Jane Rylett (welcome remarks), Dr. Stephanie A. Studenski (speaker), Dr. Timothy Doherty (speaker), Dr. Aleksandra Zecevic (speaker), Dr. Jeffrey Jutai (speaker), Dr. David Galinsky (speaker), Dr. Richard Camicioli (speaker), Dr. Louis Bherer (speaker), and Dr. Jennie Wells (speaker).

Workshop Evaluation

The workshop evaluation was positive, with the majority of participants indicating that the workshop was a successful and worthwhile event. A quantitative anonymous evaluation conducted by the staff from CIHR-IA determined that 85% of the participants found that most of the information provided was novel to them. Eighty-three per cent of the participants also attributed the success of the workshop to the quality, diversity, and intellectual range of participants who attended the workshop. The workshop was viewed as an “excellent overview of wide ranging work in an exciting research area with major implications for clinical practice, environmental design, and quality of life for older persons.”

Respondents reported that 90% of the information was useful. The dynamic of the group interaction and round-table discussion was a highlight for the respondents and the engagement with the experts was applauded. “There was great breadth and depth in each of the speakers discussions” reported one student workshop participant, and this sentiment was shared among most respondents. Overall, the workshop was a successful day of learning, sharing, and building knowledge together. It was a novel creative process where community and industry, science and clinical experience collaborated and worked towards developing a plan to create intervention for future populations of seniors while assisting those who are currently afflicted with mobility and cognition deficits.


Canadian Geriatrics Journal, Vol. 18, No. 3, September 2015