Quality Improvement Project to Reduce Drug-Related Problems (DRPs) and Potentially Inappropriate Medications (PIMs) in Geriatrics Cardiac Clinic in Saudi Arabia

Sanaa S. Mekdad, Alaa A. Alsayed



Elderly people have a high risk of potentially inappropriate medications (PIMs) and drug-related problems (DRPs) due to polypharmacy, physical and mental limitations, pharma-cokinetic, and pharmacodynamics changes.

To determine the role of geriatric pharmacists in reducing drug- related problems and potentially inappropriate medication.


The observational study was conducted from October 2014 to October 2017 to show the prevalence of DRPs, and PIMs. A total of 375 geriatric cardiology patients (aged ≥ 65) were recruited from Geriatrics Cardiac Clinic in Saudi Arabia. AGS Beers Criteria 2012 and STOPP/START Criteria were used to view the impact of services directed by clinical pharmacists in decreasing DRPs and PIMs including medication review, intervention, and education to junior physicians during multi-disciplinary rounds (MDRs) and by sending e-mail alerts.


DRPs were found in 29.6% of patients and PIMs were found in 19% of patients. After medication review, 25% required interventions and the majority (89%) of interventions were accepted by the managing team. DRPs were found in 14.9% of patients and PIMs were found in 9.6% of the patients. DRPs and PIMs were reduced almost by 50% by reviewing the files and educating the involved physicians.


This prospective study confirms a high prevalence of DRPs and PIMs in Saudi elderly cardiac patients.


cardiac; drug-related problems; geriatrics; potentially inappropriate medication

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DOI: https://doi.org/10.5770/cgj.22.338


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ISSN: 1925-8348 (Online)